osteogenesis imperfecta fetal ultrasound case reports

collage and description by talented Dr ALAA OBEID

Osteogenesis imperfecta (OI) is a genetic disorder that prevents the body from building strong bones. That’s why it’s also called brittle bone disease.

Type II: This is the most severe type. The collagen is not formed normally. Babies with type II are usually born with many fractures, are very small, and have severe breathing problems. As a result, most do not survive.
The prognosis of type II is very unfavorable, mainly due to pulmonary insufficiency ralated to the small thorax and rib fractures. Types І and ІІІ are compatible with life, but patients may develop significant complications connected with multiple fractures and deformations. Type ІV has the most favorable prognosis, fractures and deformations are rare